A 68-year-old man died of the novel coronavirus in Thiruvananthapuram, taking the number of COVID-19 deaths in Kerala to two, the government said.
The condition of the man was "extremely critical", a press release from the state-run Thiruvananthapuram Medical College and Hospital said.
The patient from nearby Pothencode, was on ventilator support for the past five days and was suffering from high blood pressure. He was also on dialysis, it said.
The man had not gone abroad and it is not yet certain how he had contracted the virus. The man had been admitted to the hospital on March 23 due to fever. Though he tested negative on March 26, in the second test on March 29 he was found positive for the virus.
The samples of the deceased's wife and daughter have been sent for testing and the results are awaited.
The man had attended a wedding and funeral before he fell ill.
The first coronavirus death in the state was reported from Chullikal in Kochi.